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Retinoids and epigenetic silencing in cancer.

Authors
Type
Published Article
Journal
Nutrition reviews
Publication Date
Volume
61
Issue
8
Pages
284–289
Identifiers
PMID: 13677591
Source
Medline
License
Unknown

Abstract

An epigenetic event alters the activity of genes without changing their structure. Methylation reactions are important mediators of epigenetic events in cells. Two recent studies have established a mechanistic link between a vitamin A metabolite and epigenetic alterations of its target promoter that could provide insights about the role of vitamin A in cancer prevention.

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