Affordable Access

Retinal angiogenesis in development and disease.

Authors
  • Gariano, Ray F
  • Gardner, Thomas W
Type
Published Article
Journal
Nature
Publisher
Springer Nature
Publication Date
Dec 15, 2005
Volume
438
Issue
7070
Pages
960–966
Identifiers
PMID: 16355161
Source
Medline
License
Unknown

Abstract

The retina has long been regarded as 'an approachable part of the brain' for investigating neurosensory processes. Cell biologists are now capitalizing on the accessibility of the retina to investigate important aspects of developmental angiogenesis, including how it relates to neuronal and glial development, morphogenesis, oxygen sensing and progenitor cells. Pathological angiogenesis also occurs in the retina and is a major feature of leading blinding diseases, particularly diabetic retinopathy. The retina and its clinical disorders have a pivotal role in angiogenesis research and provide model systems in which to investigate neurovascular relationships and angiogenic diseases.

Report this publication

Statistics

Seen <100 times