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Resuscitation from hemorrhagic shock: fluid selection and infusion strategy drives unmeasured ion genesis.

Authors
  • Kaplan, Lewis J
  • Philbin, Nora
  • Arnaud, Francoise
  • Rice, Jennifer
  • Dong, Feng
  • Freilich, Daniel
Type
Published Article
Journal
Journal of Trauma and Acute Care Surgery
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jul 01, 2006
Volume
61
Issue
1
Identifiers
PMID: 16832254
Source
Medline
License
Unknown

Abstract

HBOC resuscitation required the least fluid. Unmeasured anions were prevalent in HEX and NON (+ SIG), whereas HBOC liberated unmeasured cations (- SIG); differences were inapparent when only evaluating pH. Only HBOC increased the SID, electrochemically promoting alkalosis. Resuscitation fluid differences may aid care in high lactate conditions where an induced counterbalancing metabolic alkalosis may be beneficial.

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