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[Results of a retrospective study on radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma].

Authors
  • Ghorbal, L1
  • Hdiji, A2
  • Ben Salah, H2
  • Elloumi, F2
  • Frikha, M3
  • Elloumi, M4
  • Daoud, J2
  • 1 Service de radiothérapie carcinologique, CHU Habib-Bourguiba, avenue Majida-Boulila, 3027 Sfax, Tunisie. Electronic address: [email protected]ahoo.fr.
  • 2 Service de radiothérapie carcinologique, CHU Habib-Bourguiba, avenue Majida-Boulila, 3027 Sfax, Tunisie.
  • 3 Service de carcinologie médicale, CHU Habib-Bourguiba, avenue Majida-Boulila, 3089 Sfax, Tunisie.
  • 4 Service d'hématologie clinique, CHU Hédi-Chaker, route El Ain, 3027 Sfax, Tunisie.
Type
Published Article
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Publication Date
Dec 01, 2018
Volume
22
Issue
8
Pages
763–766
Identifiers
DOI: 10.1016/j.canrad.2018.02.001
PMID: 30337049
Source
Medline
Keywords
Language
French
License
Unknown

Abstract

We aimed to evaluate therapeutic results of radiotherapy for gastric mucosa-associated lymphoid tissue (MALT) lymphomas. We reviewed retrospectively the records of 11 patients presenting with gastric MALT lymphoma treated between 1993 and 2014. Patients with low-grade lymphoma in failure after helicobacter eradication had exclusive gastric external radiotherapy. Chemotherapy followed by radiotherapy were indicated in case of high grade lymphoma. Radiotherapy doses range between 30 and 40Gy (2Gy per fraction, five fractions per week). All tumours were IE stage. Seven patients with low-grade lymphoma had radiotherapy. Four patients with high-grade lymphoma received chemotherapy then radiotherapy. Ten patients are in complete remission after treatment achievement. Five and 10 years disease-free survival are 100%. No severe toxicity was seen. Eradication of Helicobacter pylori is the mainstay of treatment of gastric MALT. External irradiation is an effective and well-tolerated treatment modality in case of resistance to helicobacter eradication. Copyright © 2018 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

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