We present a framework to compute the responses of hadron masses to the chemical potential in lattice QCD simulations. As a first trial, the screening mass of the pseudoscalar meson and its first and second responses are evaluated. We present results on a $16\times 8^2\times 4$ lattice with two flavors of staggered quarks below and above $T_c$. The responses to both the isoscalar and isovector chemical potentials are obtained. They show different behavior in the low and the high temperature phases, which may be explained as a consequence of chiral symmetry breaking and restoration, respectively.