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The research progress of LncRNA involved in the regulation of inflammatory diseases.

Authors
  • Liao, Kaili1
  • Xu, Jiasheng2
  • Yang, Weiming1
  • You, Xiahong1
  • Zhong, Qionghui1
  • Wang, Xiaozhong3
  • 1 Department of Clinical Laborotory, The Second Affiliated Hospital of Nanchang University, China; Jiangxi Province Key Laboratory of Laboratory Medicine, China. , (China)
  • 2 Department of Vascular Surgery, The Second Affiliated Hospital of Nanchang University, China. , (China)
  • 3 Department of Clinical Laborotory, The Second Affiliated Hospital of Nanchang University, China; Jiangxi Province Key Laboratory of Laboratory Medicine, China. Electronic address: [email protected] , (China)
Type
Published Article
Journal
Molecular immunology
Publication Date
Sep 01, 2018
Volume
101
Pages
182–188
Identifiers
DOI: 10.1016/j.molimm.2018.05.030
PMID: 30007227
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Long non-coding RNA (lncRNA)is a non-coding RNA which lacks a complete open reading frame(ORF) and plays an important role in biological processes such as cell proliferation,differentiation and apoptosis. At present,the expression of lncRNA has been found to be abnormal in inflammatory reaction and inflammatory diseases. It might be involved in the development and progression of inflammatory diseases by regulating the expression of multiple genes and activation of signaling pathways. This article overviewed the progress in study on relationship between lncRNA and inflammatory diseases. Copyright © 2018 Elsevier Ltd. All rights reserved.

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