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Repeated Oral Exposure to N ε-Carboxymethyllysine, a Maillard Reaction Product, Alleviates Gut Microbiota Dysbiosis in Colitic Mice.

Authors
  • ALJahdali, Nesreen1
  • Gadonna-Widehem, Pascale2
  • Delayre-Orthez, Carine2
  • Marier, David2
  • Garnier, Benjamin2
  • Carbonero, Franck3, 4
  • Anton, Pauline M2
  • 1 Cell and Molecular Biology Program, University of Arkansas, 2650 Young Avenue, Fayetteville, AR, 72704, USA.
  • 2 Expression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France. , (France)
  • 3 Cell and Molecular Biology Program, University of Arkansas, 2650 Young Avenue, Fayetteville, AR, 72704, USA. [email protected]
  • 4 Department of Food Science and Center for Human Nutrition, University of Arkansas, 2650 Young Avenue, Fayetteville, AR, 72704, USA. [email protected]
Type
Published Article
Journal
Digestive Diseases and Sciences
Publisher
Springer-Verlag
Publication Date
Dec 01, 2017
Volume
62
Issue
12
Pages
3370–3384
Identifiers
DOI: 10.1007/s10620-017-4767-8
PMID: 28965192
Source
Medline
Keywords
License
Unknown

Abstract

Repeated oral exposure to CML limits dysbiosis in experimental colitis. IBD patients may modulate their microbiota profile by regulating the level and type of dietary MRP consumption.

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