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Repeated botulinum toxin injection for idiopathic overactive bladder: will chemodenervation become a long-term solution?

Authors
  • Unwala, Darius J
  • Barboglio, Paholo
  • Gousse, Angelo E
Type
Published Article
Journal
Current urology reports
Publication Date
Sep 01, 2007
Volume
8
Issue
5
Pages
419–424
Identifiers
PMID: 17880843
Source
Medline
License
Unknown

Abstract

Botulinum toxin A (BTX-A) has emerged as a novel treatment option for idiopathic overactive bladder (OAB) refractory to antimuscarinic agents. The clinical needs of refractory OAB patients have been recently met by sacral neuromodulation and augmentation enterocystoplasty. Important features of BTX-A should include safety, efficacy, and ease of delivery during long-term repeated usage. This article reviews the role of repeated BTX-A injections in the treatment of idiopathic OAB.

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