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Renal Hemodialysis and Maternal Serum Triple Analyte Screening

Authors
  • Shulman, Lee P.
  • Briggs, Rodney
  • Phillips, Owen P.
  • Friedman, Steven A.
  • Sibai, Baha
Type
Published Article
Journal
Fetal Diagnosis and Therapy
Publisher
S. Karger AG
Publication Date
Feb 01, 1998
Volume
13
Issue
1
Pages
26–28
Identifiers
DOI: 10.1159/000020796
Source
Karger
Keywords
License
Green
External links

Abstract

The obstetrical management of women with renal disease is complicated and associated with increased fetal and maternal morbidity. However, maternal serum screening is an integral part of obstetrical care and should be offered to all women. We found that maternal serum levels of α-fetoprotein and human chorionic gonadotropin did not significantly change as a result of hemodialysis, whereas levels of unconjugated estriol were markedly decreased following hemodialysis. Maternal serum screening should be limited to α-fetoprotein analysis in women undergoing hemodialysis until the effects of hemodialysis on all serum analytes are better delineated.

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