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Renal effects of chronic exposure to organic solvents. A clinical controlled trial.

Authors
  • Krusell, L
  • Nielsen, H K
  • Baelum, J
  • Lundqvist, G
  • Omland, O
  • Vaeth, M
  • Husted, S E
  • Mogensen, C E
  • Geday, E
Type
Published Article
Journal
Acta medica Scandinavica
Publication Date
Jan 01, 1985
Volume
218
Issue
3
Pages
323–327
Identifiers
PMID: 3907289
Source
Medline
License
Unknown

Abstract

Chronic effects of organic solvents on renal function were measured by creatinine clearances and urinary excretion rates of beta 2-microglobulin and albumin. Forty-three male printing trade workers occupationally exposed to different organic solvents for 9-25 years were compared with 43 age-matched male controls. No differences were found either in creatinine clearances or average basal levels of beta 2-microglobulin and albumin excretion rates, whereas a positive relation could be demonstrated between alcohol consumption on the day before the trial and urinary excretion rate of albumin. This investigation did not reveal any adverse renal effects of moderate chronic exposure to organic solvents in a group of active trade workers.

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