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Remodeling of the arterial wall: Response to restoration of normal blood flow after flow reduction.

Authors
  • Hayashi, Kozaburo1
  • Kakoi, Daichi1
  • Makino, Akihisa1
  • 1 Department of Mechanical Science and Bioengineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka, Japan. , (Japan)
Type
Published Article
Journal
Biorheology
Publication Date
Jan 01, 2018
Volume
54
Issue
2-4
Pages
95–108
Identifiers
DOI: 10.3233/BIR-17146
PMID: 29376846
Source
Medline
Keywords
License
Unknown

Abstract

Arteries change diameters in response to BF reduction and also flow restoration to normal after flow reduction, keeping WSS at physiologically normal levels. The lack of changes in vascular elasticity suggests that there were no significant changes in major wall constituents, such as elastin and collagen. VSM may play the dominant role in observed arterial remodeling and adaptation.

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