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Remission of relapsing childhood nephrotic syndrome with mycophenolate mofetil.

Authors
Type
Published Article
Journal
Pediatric nephrology (Berlin, Germany)
Publication Date
Volume
14
Issue
3
Pages
224–226
Identifiers
PMID: 10752763
Source
Medline
License
Unknown

Abstract

We report a 21-year-old male with childhood-onset familial nephrotic syndrome and frequent relapses who manifested toxicity or treatment resistance to corticosteroids, cyclophosphamide, cyclosporin-A, and tacrolimus. Monotherapy with mycophenolate mofetil (MMF) resulted in maintenance of clinical remission for 14 months without noticeable toxicity, while allowing resolution of steroid-induced side effects. Our observation suggests that MMF may be useful in maintaining remission in nephrotic patients who manifest toxicity to standard immunosuppressive agents.

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