Affordable Access

Remifentanil and fentanyl during anaesthesia for major abdominal and gynaecological surgery. An open, comparative study of safety and efficacy.

Authors
  • Sneyd, J R
  • Camu, F
  • Doenicke, A
  • Mann, C
  • Holgersen, O
  • Helmers, J H
  • Appelgren, L
  • Noronha, D
  • Upadhyaya, B K
Type
Published Article
Journal
European journal of anaesthesiology
Publication Date
Sep 01, 2001
Volume
18
Issue
9
Pages
605–614
Identifiers
PMID: 11553256
Source
Medline
License
Unknown

Abstract

Anaesthesia combining isoflurane with a continuous infusion of remifentanil was significantly more effective than fentanyl at blunting responses to surgical stimuli. Significantly fewer patients responded to tracheal intubation with remifentanil at 0.4 microg kg(-1) min(-1), supporting the use of a higher initial infusion rate before intubation. Both remifentanil and fentanyl were well-tolerated, with reported adverse events typical of mu-opioid agonists.

Report this publication

Statistics

Seen <100 times