A reliable method for establishing viral infection in the rabbit by intranasal inoculation.
Department of Clinical Veterinary Medicine, University of Cambridge, U.K.
- Published Article
Journal of Virological Methods
- Publication Date
Mar 01, 1990
Bovine herpesvirus 1 (BHV-1) infection was established in the rabbit by a novel procedure which involved virus being injected through trephine openings on either side of the nose of anaesthetised animals. This method of intranasal inoculation produced more consistent reactions to BHV-1 inoculation, and both humoral and cell-mediated immune responses to the virus were of greater magnitude compared with those following per naris instillation of virus.
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This record was last updated on 04/19/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/2157733