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The release of oxytocin from spinal cord synaptosomes by high KCl depolarizing stimulus: a calcium dependent process.

Authors
  • Daddona, M M
  • Haldar, J
Type
Published Article
Journal
Life Sciences
Publisher
Elsevier
Publication Date
Jan 01, 1994
Volume
54
Issue
14
Pages
945–949
Identifiers
PMID: 8139384
Source
Medline
License
Unknown

Abstract

Oxytocin (OT) release from synaptosomes isolated from the thoracic (T) and lumbosacral (LS) regions of the spinal cord was evoked by 56 mM potassium chloride (KCl). The release mechanism was shown to be a calcium dependent process. The ability of high KCl to evoke OT release from isolated nerve terminals in a calcium dependent manner provides additional support for the role of OT as a neurotransmitter in the spinal cord.

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