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Release of merozoite dense granules during erythrocyte invasion by Plasmodium knowlesi.

Authors
Type
Published Article
Journal
Infection and Immunity
0019-9567
Publisher
American Society for Microbiology
Publication Date
Volume
57
Issue
10
Pages
3230–3233
Identifiers
PMID: 2777381
Source
Medline

Abstract

We used immunoelectron microscopy to study the fate of dense granules during the invasion of erythrocytes by Plasmodium knowlesi merozoites. When merozoites entered host cells, dense granules moved to the pellicle, released their contents into the parasitophorous vacuole space, and then moved into fingerlike channels of the vacuole membrane. This is the first report showing that the content of dense granules of P. knowlesi is different from the contents of rhoptries and micronemes and is associated with the formation of channels from the parasitophorous vacuole.

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