Intrahepatic metastasis of HCC depends very much on its in situ microenvironment. The decline in nm23-H1 mRNA may implicate a preferential proliferation of nm23-negetive HCC cells with highly metastastic potential which adapt well to the microenvironment.
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This record was last updated on 07/02/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/10921047