Affordable Access

deepdyve-link
Publisher Website

Relationship between white matter microstructure and work hours.

Authors
  • Matsumoto, Junya1
  • Fukunaga, Masaki2
  • Miura, Kenichiro1
  • Nemoto, Kiyotaka3
  • Koshiyama, Daisuke4
  • Okada, Naohiro5
  • Morita, Kentaro6
  • Yamamori, Hidenaga7
  • Yasuda, Yuka8
  • Fujimoto, Michiko9
  • Hasegawa, Naomi1
  • Watanabe, Yoshiyuki10
  • Kasai, Kiyoto5
  • Hashimoto, Ryota11
  • 1 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan. , (Japan)
  • 2 Division of Cerebral Integration, National Institute for Physiological Sciences, 38 Nishigonaka Myodaiji, Okazaki, Aichi 444-8585, Japan. , (Japan)
  • 3 Department of Psychiatry, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan. , (Japan)
  • 4 Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. , (Japan)
  • 5 Department of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Department of Neuropsychiatry, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan; The International Research Center for Neurointelligence (WPI-IRCN) at University of Tokyo Institutes for Advanced Study (UTIAS), 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. , (Japan)
  • 6 Department of Rehabilitation, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. , (Japan)
  • 7 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan; Japan Community Health Care Organization Osaka Hospital, 4-2-78 Fukushima, Fukushima-ku, Osaka, Osaka 553-0003, Japan; Department of Psychiatry, Osaka University, Graduate School of Medicine, D3, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan. , (Japan)
  • 8 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan; Medical Corporation Foster, 1-3-11, Oyodominami, Kita-ku, Osaka, Osaka, 531-0075, Japan. , (Japan)
  • 9 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan; Department of Psychiatry, Osaka University, Graduate School of Medicine, D3, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan. , (Japan)
  • 10 Department of Radiology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan. , (Japan)
  • 11 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan; Osaka University, 1-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: [email protected] , (Japan)
Type
Published Article
Journal
Neuroscience letters
Publication Date
Oct 18, 2020
Pages
135428–135428
Identifiers
DOI: 10.1016/j.neulet.2020.135428
PMID: 33086092
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Human social activities are realized by a synergy of neuronal activity over various regions of the brain, which is supported by their connectivity. In the present study, we examined associations between social activities, represented by work hours, and brain connectivity as quantified using diffusion tensor imaging (DTI). In 483 healthy participants, DTI analysis was performed using 3 T magnetic resonance imaging, and work hours were calculated, considering hours of paid employment (the "Work for Pay" category), hours of housework (the "Work at Home" category), and hours of school-related study (the "Student" category). The correlations between each class of work time and DTI indices were analyzed. The mean diffusivity (MD) values of the anterior limb of the internal capsule (ALIC) and the superior fronto-occipital fasciculus (SFO) were negatively correlated with total work hours (ALIC: r = -0.192, p = 2.3 × 10-5; SFO: r = -0.161, p = 3.8 × 10-4). We also found that the MD values of the ALIC and the SFO were correlated with work hours in the Work for Pay category (ALIC: r = -0.211, p = 3.2 × 10-6; SFO: r = -0.163, p = 3.4 × 10-4) but not with those in the Work at Home category or the Student category. These results suggest that social activity is associated with the white matter microstructure of the ALIC and the SFO. The main difference between "Work for Pay" and the other two social activities appears to be the type of motivation-for example, external versus internal. Therefore, the white matter microstructure of the ALIC and SFO may be related to externally motivated social activities. Copyright © 2020. Published by Elsevier B.V.

Report this publication

Statistics

Seen <100 times