Relationship Between Serum Levels of Arsenic, Cadmium, and Mercury and Body Mass Index and Fasting Plasma Glucose in a Mexican Adult Population.

Héctor Hernández-Mendoza; Héctor Edmundo Álvarez-Loredo; Elizabeth Teresita Romero-Guzmán; Darío Gaytán-Hernández; Consuelo Chang-Rueda; Israel Martínez-Navarro; Bertha Irene Juárez-Flores; María Judith Rios-Lugo

doi:10.1007/s12011-021-03081-7

Publisher Website

Relationship Between Serum Levels of Arsenic, Cadmium, and Mercury and Body Mass Index and Fasting Plasma Glucose in a Mexican Adult Population.

Authors

Hernández-Mendoza, Héctor^{1, 2}
Álvarez-Loredo, Héctor Edmundo³
Romero-Guzmán, Elizabeth Teresita⁴
Gaytán-Hernández, Darío⁵
Chang-Rueda, Consuelo⁶
Martínez-Navarro, Israel³
Juárez-Flores, Bertha Irene⁷
Rios-Lugo, María Judith^{8, 9}

¹ Instituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, Altair 200, C.P: 78377, San Luis Potosí, S.L.P., México. [email protected]
² Universidad del Centro de México, Capitán Caldera 75, C.P: 78250, San Luis Potosí, S.L.P., México. [email protected]
³ Centro de Investigación en Ciencias de Salud y Biomedicina, Sección de Medicina Molecular y Traslacional, Universidad Autónoma de San Luis Potosí, Avda Sierra Leona 550, C.P: 78210, San Luis Potosí, S.L.P., México.
⁴ Departamento de Química, Gerencia de Ciencias Básicas, Dirección de Investigación Científica, Carretera México-Toluca S/N, C.P: 52750, La Marquesa Ocoyoacác, México.
⁵ Facultad de Enfermería Y Nutrición, Unidad de Posgrado, Universidad Autónoma de San Luis Potosí, Avda. Niño Artillero 130, C.P: 78210, San Luis Potosí, S.L.P., México.
⁶ Facultad de Ciencias Químicas, Universidad Autónoma de Chiapas, Campus IV Carretera a Puerto Madero Km 1.5, C.P: 30580, Tapachula, Chiapas, México.
⁷ Instituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, Altair 200, C.P: 78377, San Luis Potosí, S.L.P., México.
⁸ Centro de Investigación en Ciencias de Salud y Biomedicina, Sección de Medicina Molecular y Traslacional, Universidad Autónoma de San Luis Potosí, Avda Sierra Leona 550, C.P: 78210, San Luis Potosí, S.L.P., México. [email protected]
⁹ Facultad de Enfermería Y Nutrición, Unidad de Posgrado, Universidad Autónoma de San Luis Potosí, Avda. Niño Artillero 130, C.P: 78210, San Luis Potosí, S.L.P., México. [email protected]

Type

Published Article

Journal

Biological Trace Element Research

Publisher

Springer-Verlag

Publication Date

Dec 01, 2022

Volume

200

Issue

12

Pages

4916–4923

Identifiers

DOI: 10.1007/s12011-021-03081-7

PMID: 35098445

Source

Medline

Keywords

Language

English

License

Unknown

Abstract

In Mexico, few studies have analyzed the associations between toxic elements and metabolic diseases. In the present study, we analyzed the associations between serum arsenic (As), cadmium (Cd), and mercury (Hg) levels and body mass index (BMI) and fasting plasma glucose (FPG) in a Mexican adult population. Anthropometric data corresponding to 86 Mexican healthy adults (59 females and 27 men) were analyzed. FPG was analyzed by an enzymatic colorimetric method, and serum As, Cd, and Hg levels were analyzed by inductively coupled plasma-mass spectrometry (ICP-MS). The data show that the median serum As, Cd, and Hg levels were relatively higher in females (As = 1.78 ng mL-1, Cd = 1.00 ng mL-1, Hg = 0.96 ng mL-1) than those in males (As = 1.22 ng mL-1, Cd = 0.91 ng mL-1, Hg = 0.95 ng mL-1). However, these differences were not statistically significant (p ≥ 0.097). We also found that the median level of As significantly increased with an increase in the body weight categories (normal weight = 1.08; overweight = 1.50; obesity = 2.75; p < 0.001). In addition, a positive association between serum As levels and FPG before and after adjustment for BMI was demonstrated (RhoUnadjusted = 0.012; (RhoAdjusted = 0.243, p = 0.032). Serum As levels are positively associated with BMI and FPG in the adult population of Mexico. Nevertheless, these results need to be replicated and confirmed with a larger sample size. © 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. This record was last updated on 12/19/2022 and may not reflect the most current and accurate biomedical/scientific data available from NLM. The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/35098445

Report this publication

Statistics

Seen <100 times