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Relationship between exhaled nitric oxide and IgE sensitisation in patients with asthma: influence of steroid treatment.

Authors
Type
Published Article
Journal
The Clinical Respiratory Journal
1752-699X
Publisher
Wiley Blackwell (Blackwell Publishing)
Publication Date
Volume
3
Issue
3
Pages
143–151
Identifiers
DOI: 10.1111/j.1752-699X.2008.00124.x
PMID: 20298397
Source
Medline
License
Unknown

Abstract

Serum IgE against perennial allergens and FE(NO) correlate in patients with allergic asthma. However, this relationship disappears after a high-dose ICS regimen, suggesting that FE(NO) relates to bronchial inflammation and not IgE levels per se. High degree of IgE sensitisation together with allergen exposure may lead to ICS-resistant airways inflammation.

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