Affordable Access

Regulation of MMP-1 by sex steroid hormones in fibroblasts derived from the female pelvic floor.

Authors
  • Zong, Wenjun
  • Zyczynski, Halina M
  • Meyn, Leslie A
  • Gordy, Susan C
  • Moalli, Pamela A
Type
Published Article
Journal
American Journal of Obstetrics and Gynecology
Publisher
Elsevier
Publication Date
Apr 01, 2007
Volume
196
Issue
4
Identifiers
PMID: 17403418
Source
Medline
License
Unknown

Abstract

Fragmentation is a site of regulation of MMP-1 expression by hormones. Only E2 combined with progesterone decreased the active form of MMP-1, which suggests that both hormones are necessary to maintain the integrity of female pelvic floor.

Report this publication

Statistics

Seen <100 times