Information is essential for the taking care of the patients and is also a guarantee for the quality of cares. In this objective, the University Hospital of Lille has developed for 10 years a politic based on information and communication divided in 3 phases: 1. The University Hospital has developed a HIS based on the communication between hospitals and medical centers for a better sharing of data concerning the patient. 2. The second phase consisted in the integration of external platforms to the HIS with a middleware. 3. The actual phase consists in the opening of the HIS to the external environment of the hospital and especially to the GPs through a Regional Medical Information System.