Affordable Access

Regional myocardial oxygen tension: 19F MRI of sequestered perfluorocarbon.

Authors
Type
Published Article
Journal
Magnetic resonance in medicine
Publication Date
Volume
35
Issue
6
Pages
827–833
Identifiers
PMID: 8744009
Source
Medline

Abstract

A novel noninvasive method of measuring local myocardial oxygen tension (pO2) in the perfused rat heart using 19F MRI is demonstrated. Tissue pO2 was determined on the basis of the 19F spin-lattice relaxation rate (R1) of perflubron (perfluorooctyl bromide) sequestered in the heart after IV infusion of an emulsion. Spectroscopic measurement of R1 was previously used to measure a global weighted average of oxygen status. 19F MRI now provides 3D spatial resolution indicating local cardiac pO2 under normally perfused, globally ischemic, and regionally ischemic conditions.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments