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Regional brain activation during proximal stomach distention in humans: A positron emission tomography study.

Authors
  • Vandenbergh, Joris
  • Dupont, Patrick
  • Fischler, Benjamin
  • Bormans, Guy
  • Persoons, Philippe
  • Janssens, Jozef
  • Tack, Jan
Type
Published Article
Journal
Gastroenterology
Publisher
Elsevier
Publication Date
Mar 01, 2005
Volume
128
Issue
3
Pages
564–573
Identifiers
PMID: 15765391
Source
Medline
License
Unknown

Abstract

We found evidence for a neuronal network processing distention stimuli of the proximal stomach that is overall consistent with the "visceral stimulation network" described in the literature. In addition, we found activation of the orbitofrontal cortex, confirming its role as a convergence zone for processing of food-related stimuli and regulation of hunger, appetite, satiety, and food intake. We found no evidence for a functional neuroanatomic divergence in the processing of noxious and innocuous gastric stimuli.

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