In recent years, the safety of oil and gas storage and transportation facilities has been paid more attention by the state and enterprises due to frequent accidents. The oil and gas storage and transportation facilities safety courses in China University of Petroleum (Beijing) includes “Engineering mechanics”, “Strength design of pipelines and tanks” and “Safety and integrity management of oil and gas storage and transportation facilities”. The three courses lack relevance and the teaching mode is too rigid, resulting in students losing their initiative in learning. If students can’t use the knowledge flexibly, it will affect the achievement of the objectives of the training program. Therefore, oil and gas storage and transportation facilities safety courses are reformed, training plans are adjusted and teaching methods are improved. The practice shows that the reform enriches the teaching content, improves the teaching quality, stimulates classroom activity and gets a good evaluation of students. The reform of safety courses has a certain significance for cultivating compound talents who have the ability to solve practical problems in engineering.