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Reduction of Diffusion-Weighted Imaging Contrast of Acute Ischemic Stroke at Short Diffusion Times.

Authors
  • Baron, Corey Allan
  • Kate, Mahesh
  • Gioia, Laura
  • Butcher, Kenneth
  • Emery, Derek
  • Budde, Matthew
  • Beaulieu, Christian
Type
Published Article
Journal
Stroke
Publisher
Ovid Technologies Wolters Kluwer -American Heart Association
Publication Date
Aug 01, 2015
Volume
46
Issue
8
Pages
2136–2141
Identifiers
DOI: 10.1161/STROKEAHA.115.008815
PMID: 26152297
Source
Medline
Keywords
License
Unknown

Abstract

Short diffusion times result in dramatically reduced diffusion contrast of human stroke. Simulations implicate a combination of neuronal beading and axonal swelling as the key structural changes leading to the reduced apparent diffusion coefficient after stroke.

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