Reduced plasma antioxidant concentrations and increased oxidative DNA damage in inflammatory bowel disease.
Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Università di Padova, Italy. [email protected]
- Published Article
Scandinavian journal of gastroenterology
- Publication Date
Dec 01, 2001
Depletion of antioxidants is likely to be important in the pathophysiology of IBD: UC and CD patients show increased free radical peripheral leukocyte DNA damage and decreased plasma antioxidant defenses. These results indicate the necessity of further studies to establish whether optimal vitamin status may improve the clinical course of UC and CD.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/11761019