Affordable Access

Reduced plasma antioxidant concentrations and increased oxidative DNA damage in inflammatory bowel disease.

Authors
  • 1
  • 1 Dipartimento di Scienze Chirurgiche e Gastroenterologiche, Università di Padova, Italy. [email protected] , (Italy)
Type
Published Article
Journal
Scandinavian journal of gastroenterology
Publication Date
Volume
36
Issue
12
Pages
1289–1294
Identifiers
PMID: 11761019
Source
Medline
License
Unknown

Abstract

Depletion of antioxidants is likely to be important in the pathophysiology of IBD: UC and CD patients show increased free radical peripheral leukocyte DNA damage and decreased plasma antioxidant defenses. These results indicate the necessity of further studies to establish whether optimal vitamin status may improve the clinical course of UC and CD.

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