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Reduced apoptosis by pentoxiphylline among patients with HIV infection.

Authors
  • Wanchu, A
  • Bhatnagar, A
  • Kumar, B
  • Bambery, P
  • Singh, S
Type
Published Article
Journal
International Immunopharmacology
Publisher
Elsevier
Publication Date
Mar 01, 2003
Volume
3
Issue
3
Pages
359–364
Identifiers
PMID: 12639813
Source
Medline
License
Unknown

Abstract

Therapy with pentoxiphylline for 24 weeks is associated with a decline in the levels of caspase 1 and caspase 8. Since the drug is known to produce TNF inhibition, this might result in reduced apoptosis and an improved CD4 lymphocyte survival.

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