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[Redox status in HIV+ patients under HAART].

Authors
  • Flourié, F
  • Arab, K
  • Gagnieu, M C
  • Tardy, J C
  • Jeanblanc, F
  • Livrozet, J M
  • Steghens, J P
Type
Published Article
Journal
Annales de biologie clinique
Publication Date
Jan 01, 2004
Volume
62
Issue
6
Pages
713–715
Identifiers
PMID: 15563432
Source
Medline
License
Unknown

Abstract

Oxidative stress decreases immune defences and is also suggested to participate in the activation of HIV virus replication. That is why we decided to explore some biomarkers of oxidative stress (reduced glutathione, lipoperoxides, true malondialdehyde and vitamin C) in 20 HIV positive patients whose HIV replication was determined by measurement of RNA viral load. Reduced glutathione is decreased in HIV positive patients, without correlation with the viral load. The patients mean content of lipoperoxides is twice that of controls but with such a large range that there is no statistical difference.

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