Affordable Access

Rediscovering Chirality - Role of S-Metoprolol in Cardiovascular Disease Management.

Authors
  • Mohan, Jagdish C1
  • Shah, Siddharth N2
  • Chinchansurkar, Sunny3
  • Dey, Arindam3
  • Jain, Rishi3
  • 1 Director and HOD Cardiology, Fortis Hospital, New Delhi.
  • 2 Honarary Consultant and Diabetologist, Saifee Hospital, S.L. Raheja Hospital, Bhatia Hospital and Sir H.N. Hospital, Mumbai, Maharashtra.
  • 3 Medical Services, Emcure Pharmaceuticals Ltd., Pune, Maharashtra.
Type
Published Article
Journal
The Journal of the Association of Physicians of India
Publication Date
Jun 01, 2017
Volume
65
Issue
6
Identifiers
PMID: 28782316
Source
Medline
License
Unknown

Abstract

Chirality is a good way forward in providing a new drug molecule which is safe with lesser pharmacokinetic and pharmacodynamics variability, lesser side effects and more potent action. S-metoprolol is chirally pure form of racemate metoprolol and has lesser side effects, is safer in patients of COPD and Diabetes who also have hypertension and comparable responder rates at half the doses when compared to racemate.

Report this publication

Statistics

Seen <100 times