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Recurrent severe anaemia: a rare presentation of parvovirus b19 infection.

Authors
  • Singh, Santokh
  • Chand, Gian
  • Charan, Shiv
  • Arora, Sahil
  • Singh, Parampreet
Type
Published Article
Journal
JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH
Publisher
JCDR Research and Publications
Publication Date
Apr 01, 2014
Volume
8
Issue
4
Identifiers
DOI: 10.7860/JCDR/2014/7840.4250
PMID: 24959472
Source
Medline
Keywords
License
Unknown

Abstract

Secondary pure red cell aplasia is usually seen in immunocompromised hosts or patients who have chronic haemolytic anaemia, which is caused by blood transfusion related transmission. The present patient, a 30-year-old immunocompetent female, presented several times with recurrent severe anaemia, over a period of one and half years. Her history, clinical examination and investigations did not reveal any indigenous drug intake, previous blood transfusions, haemolytic disorders, myeloproliferative disorders, pregnancies, autoimmune diseases or thymoma. She was found to have a thalassaemia minor trait, on the basis of which severity and recurrence of anaemia could not be explained, and on further evaluation, she was diagnosed to have acute aplastic crisis caused by Parvovirus B19 induced, acquired pure red cell aplasia. The co- existence of these two haematological disorders in an immunocompetent, non-transfusion dependent individual is rare, which makes our case report unique.

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