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The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains.

Authors
  • Mostov, K E
  • Friedlander, M
  • Blobel, G
Type
Published Article
Journal
Nature
Publication Date
Jan 01, 1984
Volume
308
Issue
5954
Pages
37–43
Identifiers
PMID: 6322002
Source
Medline
License
Unknown

Abstract

We have cloned and sequenced cDNA for the receptor that mediates the endocytosis and transcellular transport of IgA and IgM across many glandular epithelia into external secretions. This receptor contains five extracellular domains which are strikingly homologous to each other and to immunoglobulin variable regions.

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