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Recent developments in fatty acids profile determination in biological samples - a review

Authors
  • Tiuca, Ioana
  • Nagy, Katalin
  • Oprean, Radu
Type
Published Article
Journal
Revista Romana de Medicina de Laborator
Publisher
De Gruyter Open Sp. z o.o.
Publication Date
Dec 01, 2015
Volume
23
Issue
4
Pages
371–384
Identifiers
DOI: 10.1515/rrlm-2015-0035
Source
De Gruyter
Keywords
License
Green

Abstract

The present paper is a literature review of the recent years dealing with the most important separation techniques of fatty acids in biological samples. Our aim was to make a synthesis of the analytical methods used, to note the most used ones, but also to mention other methods that are less utilized, which can have important advantages (such as less time consuming, greener reagents, etc.). Gas-chromatographic separation methods were described and compared to liquid chromatographic separations of fatty acids in different types of biological samples. In the same time, the importance of determining fatty acids profiles in biological samples was revealed, pointing out the possible implications in diagnostics of different types of disorders or remarking different profiles compared to healthy states.

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