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Recent Advances of Magnetic Nanomaterials in Bone Tissue Repair

Authors
  • Fan, Daoyang1
  • Wang, Qi2
  • Zhu, Tengjiao3
  • Wang, Hufei4, 5
  • Liu, Bingchuan3
  • Wang, Yifan6
  • Liu, Zhongjun3
  • Liu, Xunyong7
  • Fan, Dongwei2
  • Wang, Xing4, 5
  • 1 Department of Orthopedic, First Affiliated Hospital of Zhengzhou University, Zhengzhou , (China)
  • 2 Department of Pediatrics, Peking University Third Hospital, Beijing , (China)
  • 3 Department of Orthopedic, Peking University Third Hospital, Beijing , (China)
  • 4 Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing , (China)
  • 5 University of Chinese Academy of Sciences, Beijing , (China)
  • 6 CED Education, North Carolina State University, Raleigh, NC , (United States)
  • 7 School of Chemistry and Materials Science, Ludong University, Yantai , (China)
Type
Published Article
Journal
Frontiers in Chemistry
Publisher
Frontiers Media S.A.
Publication Date
Sep 25, 2020
Volume
8
Identifiers
DOI: 10.3389/fchem.2020.00745
PMID: 33102429
PMCID: PMC7545026
Source
PubMed Central
Keywords
License
Unknown

Abstract

The magnetic field has been proven to enhance bone tissue repair by affecting cell metabolic behavior. Magnetic nanoparticles are used as biomaterials due to their unique magnetic properties and good biocompatibility. Through endocytosis, entering the cell makes it easier to affect the physiological function of the cell. Once the magnetic particles are exposed to an external magnetic field, they will be rapidly magnetized. The magnetic particles and the magnetic field work together to enhance the effectiveness of their bone tissue repair treatment. This article reviews the common synthesis methods, the mechanism, and application of magnetic nanomaterials in the field of bone tissue repair.

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