Catalytic oxidation is regarded as one of the most promising strategies for volatile organic compounds (VOCs) purification. Mixed metal oxides (MMOs), after topological transformation using layered double hydroxides (LDHs) as precursors, are extensively used as catalysts for VOCs oxidation due to their uniformity advantage. This review summarizes the developments in the LDH-derived VOCs heterogeneous catalytic oxidation over the last 10 years. Particularly, it addresses the VOCs abatement performance over MMO, noble metal/MMO, core-shell structured MMO, and integral MMO film catalysts originating from LDHs. Moreover, it highlights the water vapor effect and oxidation mechanism. This review indicates that LDH-based catalysts are a category of important VOCs oxidation materials. (C) 2020, Dalian Institute of Chemical Physics, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.