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Rational treatment of pulmonary infections in patients with cystic fibrosis.

Authors
  • Foca, M
  • Rajan, S
  • Saiman, L
Type
Published Article
Journal
Current opinion in infectious diseases
Publication Date
Jun 01, 1999
Volume
12
Issue
3
Pages
257–263
Identifiers
PMID: 17035789
Source
Medline
License
Unknown

Abstract

The life expectancy of patients with cystic fibrosis has increased markedly during the past two decades due in large part to improved clinical care, including the use of more effective antimicrobial agents for Pseudomonas. However, the chronic lung disease of CF remains the principal cause of mortality. A growing understanding of the complex interactions between infection and inflammation has led to new approaches for treatment, including chronic use of aerosolized antibiotics, particularly tobramycin, in patients known to be colonized/infected with P. aeruginosa and anti-inflammatory treatments to slow the progression of lung disease.

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