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Rapidly progressive, acute polyradiculopathies and cranial neuropathies resulting from leptomeningeal nasal-type NK cell lymphoma.

Authors
Type
Published Article
Journal
Journal of clinical neuromuscular disease
Publication Date
Volume
1
Issue
3
Pages
137–140
Identifiers
PMID: 19078573
Source
Medline

Abstract

Lymphomas may cause polyradiculopathies by several pathogenic mechanisms. However, such a presentation of a nasal-type NK (natural killer) cell lymphoma is rare. We report a previously healthy man who developed acute, axon-loss radiculopathies and cranial neuropathies. Despite the lack of a nasal or midline facial mass, cerebrospinal fluid cytologic and flow cytometric immurtophenotypic studies disclosed that the patient's rapid demise was the result of a nasal-type NK cell lymphoma with leptomeningeal involvement.

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