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Rapidly growing giant suprasellar tumor in a high-risk child: treatment strategy and role of neuroendoscopic surgery in slit-like ventricles

Authors
  • Abdullah, Saad Hamdan1
  • Irie, Koreaki1
  • Oi, Shizuo1
  • 1 The Jikei University School of Medicine, Division of Pediatric Neurosurgery, Women’s and Children’s Medical Center, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo, 105-8461, Japan , Tokyo
Type
Published Article
Journal
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Publication Date
Jun 17, 2005
Volume
22
Issue
4
Pages
403–408
Identifiers
DOI: 10.1007/s00381-005-1156-y
Source
Springer Nature
Keywords
License
Yellow

Abstract

RationaleSuprasellar tumors are common in the pediatric population and exhibit a wide range of pathological appearance and behavior. Although rare, pure suprasellar germinomas carry worse prognosis than other locations.MethodsWe present a case of a 10-year-old girl treated with therapeutic anticoagulation for previous cardiac valvular replacement, who presented with rapidly growing giant (>4 cm) suprasellar germinoma. Neoadjuvant chemotheraphy was effective and the dilated ventricles became slit-like. The fine free-hand maneuver using a fine rigid-rod neuroendoscope. “Oi-Samii Handy Pro” made it possible to obtain the tissue diagnosis.ResultsComplete remission was achieved using neoadjuvant chemotherapy, minimally invasive neuroendoscopic surgery, then followed by specific chemoradiotherapy.ConclusionThe role of neuroendoscopic procedure, performed in a difficult situation with normalized size of the ventricles, was emphasized.

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