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Rapid serum clot tubes reduce haemolysis due to pneumatic tube transport.

Authors
  • Koch, Christopher D1
  • Vera, Michael A1
  • El-Khoury, Joe M2
  • 1 Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
  • 2 Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, USA [email protected].
Type
Published Article
Journal
Journal of Clinical Pathology
Publisher
BMJ
Publication Date
Sep 01, 2022
Volume
75
Issue
9
Pages
643–645
Identifiers
DOI: 10.1136/jclinpath-2021-208126
PMID: 35273119
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Pneumatic tube systems (PTSs) are critical for modern hospital operations, allowing for rapid sample transport. Despite widespread use, PTSs can compromise specimen integrity and affect laboratory values. Our objective was to prove that rapid serum clot tubes (RST) provide protective benefits over plasma during PTS transport and can be a practical solution for certain PTS routes. In this study, we compared the effects of PTS transport on cell lysis indicators: h-index, lactate dehydrogenase (LDH) and potassium (K+), in RST versus lithium heparin gel separator tubes using 10 volunteers. In comparison with plasma, RST showed a median reduction in PTS-induced haemolysis of 80.4% (p=0.0049), with a reduction in post-PTS median LDH concentration (49.7%, p=0.04) and K+ concentration (50.0%, p=0.0273). This study demonstrates RST tubes can significantly reduce PTS-induced haemolysis and can be recommended for poor PTS routes. © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

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