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Rapid isolation of human kininogens.

Authors
  • Johnson, D A
  • Salvesen, G
  • Brown, M A
  • Barrett, A J
Type
Published Article
Journal
Thrombosis Research
Publisher
Elsevier
Publication Date
Oct 15, 1987
Volume
48
Issue
2
Pages
187–193
Identifiers
PMID: 3122358
Source
Medline
License
Unknown

Abstract

A rapid, two-step procedure is described for the isolation of both "high molecular weight" (H-) and "low molecular weight" (L-) plasma kininogens from a single sample of plasma. Affinity chromatography on carboxymethyl-papain-Sepharose is used, together with high-resolution anion exchange chromatography.

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