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Rapid cardiotonic effects of lipid emulsion infusion*.

Authors
  • Fettiplace, Michael R1
  • Ripper, Richard
  • Lis, Kinga
  • Lin, Bocheng
  • Lang, Jason
  • Zider, Brian
  • Wang, Jing
  • Rubinstein, Israel
  • Weinberg, Guy
Type
Published Article
Journal
Critical care medicine
Publication Date
Aug 01, 2013
Volume
41
Issue
8
Identifiers
DOI: 10.1097/CCM.0b013e318287f874
PMID: 23531591
Source
Medline
License
Unknown

Abstract

Lipid emulsion exerts rapid, positive inotropic and positive lusitropic effects in both intact animal and isolated heart models. We hypothesize that this inotropy and the resulting increase in tissue blood flow contribute to the phenomenon of lipid reversal of cardiac toxicity caused by drug overdose.

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