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Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury.

Authors
  • Matthay, Michael A
  • Brower, Roy G
  • Carson, Shannon
  • Douglas, Ivor S
  • Eisner, Mark
  • Hite, Duncan
  • Holets, Steven
  • Kallet, Richard H
  • Liu, Kathleen D
  • MacIntyre, Neil
  • Moss, Marc
  • Schoenfeld, David
  • Steingrub, Jay
  • Thompson, B Taylor
Type
Published Article
Journal
American Journal of Respiratory and Critical Care Medicine
Publisher
American Thoracic Society
Publication Date
Sep 01, 2011
Volume
184
Issue
5
Pages
561–568
Identifiers
DOI: 10.1164/rccm.201012-2090OC
PMID: 21562125
Source
Medline
License
Unknown

Abstract

These results suggest that aerosolized albuterol does not improve clinical outcomes in patients with ALI. Routine use of β₂-agonist therapy in mechanically ventilated patients with ALI cannot be recommended. Clinical trial registered with www.clinicaltrials.gov (NCT 00434993).

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