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A randomized, double-blind, placebo-controlled evaluation of the safety and efficacy of avanafil in subjects with erectile dysfunction.

Authors
  • Goldstein, Irwin
  • McCullough, Andrew R
  • Jones, Leroy A
  • Hellstrom, Wayne J
  • Bowden, Charles H
  • Didonato, Karen
  • Trask, Brenda
  • Day, Wesley W
Type
Published Article
Journal
Journal of Sexual Medicine
Publisher
Elsevier
Publication Date
Apr 01, 2012
Volume
9
Issue
4
Pages
1122–1133
Identifiers
DOI: 10.1111/j.1743-6109.2011.02629.x
PMID: 22248153
Source
Medline
License
Unknown

Abstract

Following 12 weeks of avanafil treatment without food or alcohol restrictions, significant improvements in sexual function were observed with all 3 doses of avanafil compared with placebo. Successful intercourse was observed as early as 15 minutes and >6 hours after dosing in some subjects. Avanafil was generally well tolerated for the treatment of ED.

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