Affordable Access

deepdyve-link
Publisher Website

Randomized Controlled Trial of A 12-Week Yoga-Based (Including Diet) Lifestyle vs. Dietary Intervention on Cardio-Metabolic Risk Factors and Continuous Risk Score in Indian Adults with Metabolic Syndrome.

Authors
  • Yadav, Rashmi1
  • Yadav, Raj Kumar1
  • Khadgawat, Rajesh2
  • Pandey, Ravindra Mohan3
  • Upadhyay, Ashish Datt3
  • Mehta, Nalin1
  • 1 Department of Physiology, All India Institute of Medical Sciences, New Delhi, India. , (India)
  • 2 Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India. , (India)
  • 3 Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India. , (India)
Type
Published Article
Journal
Behavioral medicine (Washington, D.C.)
Publication Date
Jan 01, 2020
Volume
46
Issue
1
Pages
9–20
Identifiers
DOI: 10.1080/08964289.2018.1538098
PMID: 30615583
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Metabolic syndrome, a prediabetic and precardiovascular pathologic condition that begins early in life, tracks into adulthood and magnifies with age. Randomized controlled trials evaluating efficacy of yoga-based lifestyle vs. dietary intervention on metabolic syndrome are lacking. Here, the efficacy of a 12-week yoga-based lifestyle intervention vs. dietary intervention on cardio-metabolic risk factors and metabolic syndrome risk scores have been assessed in Indian adults with metabolic syndrome. In this two-arm, open label, parallel group, randomized controlled trial, 260 adults (20-45 years) diagnosed with metabolic syndrome as per joint interim statement, 2009 were randomized to yoga-based (including diet) lifestyle or dietary intervention alone (n = 130, each) for 12 weeks. Primary endpoints were the 12-week changes in cardio-metabolic risk factors and metabolic risk scores. The secondary endpoints were the 12-week changes in the proportion of subjects recovered from metabolic syndrome, dietary intake, and physical activity. Intent-to-treat analysis was performed including all the subjects with baseline data with imputed missing data. Treatment × time interaction showed yoga-based lifestyle intervention had a greater treatment effect over dietary intervention by significantly reducing waist circumference, continuous metabolic syndrome z-score, and dietary intake/day while significantly increasing physical activity. High-density lipoprotein cholesterol showed a significantly greater reduction following dietary intervention than yoga-based lifestyle intervention. A significantly greater proportion of subjects recovered from metabolic syndrome in yoga-based lifestyle (45.4%) vs. dietary intervention group (32.3%). A 12-week yoga-based lifestyle intervention is more efficacious than usual dietary intervention in improving cardio-metabolic risk factor and metabolic risk score in Indian adults with metabolic syndrome.

Report this publication

Statistics

Seen <100 times