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Radiotherapy in lymphoepithelioma-like carcinoma of the skin: review of the literature and report of a recurrent and metastatic case

Authors
  • Mucha-Małecka, A.1
  • Urbanek, K.1
  • Ambicka, A.1
  • Majchrzak, P.1
  • Małecki, K.2
  • 1 Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Cracow Branch,
  • 2 University Children’s Hospital of Cracow,
Type
Published Article
Journal
Strahlentherapie Und Onkologie
Publisher
Springer Berlin Heidelberg
Publication Date
Sep 09, 2019
Volume
195
Issue
11
Pages
1028–1032
Identifiers
DOI: 10.1007/s00066-019-01516-8
PMID: 31501980
PMCID: PMC6811378
Source
PubMed Central
Keywords
License
Unknown

Abstract

Primary lymphoepithelioma-like carcinoma of the skin (LELCS) is a very rare cutaneous neoplasm. Only about 70 cases have been documented in the literature. There are no prospective data regarding treatment methods. Surgical excision is sufficient therapy in the majority of cases. Radiation therapy is sometimes used in case of recurrence or positive margins after surgery. The metastatic potential of LELCS is extremely low and only five previously documented cases of lymph node spread have been reported. We present the case of an 80-year-old male with a tumor primarily located on the lower eyelid, with two regional recurrences and cervical lymph node spread after surgery, treated with concurrent chemoradiation. According to the available data, this is the first case of lymph node spread from an eyelid location and the first nodal recurrence after surgery.

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