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Radiotherapy of incompletely resected, moderately differentiated mast cell tumors in the dog: 37 cases (1989-1993).

Authors
  • Frimberger, A E
  • Moore, A S
  • LaRue, S M
  • Gliatto, J M
  • Bengtson, A E
Type
Published Article
Journal
Journal of the American Animal Hospital Association
Publication Date
Jan 01, 1997
Volume
33
Issue
4
Pages
320–324
Identifiers
PMID: 9204467
Source
Medline
License
Unknown

Abstract

Thirty-seven dogs with moderately differentiated, cutaneous mast cell tumors had incomplete surgical excisions as determined by histopathology, but no gross evidence of tumor. All dogs were irradiated to a total dose of between 46.2 and 48.0 Gy using either an orthovoltage source (n = 20) or a linear accelerator (megavoltage) (n = 17). Radiation was delivered to an area bordered by margins of 3 cm or greater around the surgical scar. The mast cell tumors had not recurred in 97% of dogs by one year after radiation therapy and had not recurred in 93% of dogs by three years after radiation. Both orthovoltage and megavoltage radiation provide excellent local control of moderately differentiated mast cell tumors in dogs.

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