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The radiologic progression of ameloblastomas.

Authors
  • Merbold, Lene1
  • Smit, Chané1
  • Ker-Fox, Jason2
  • Uys, Andre3
  • 1 Department of Oral and Maxillofacial Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. , (South Africa)
  • 2 Private Statistician, Cape Town, South Africa. , (South Africa)
  • 3 Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa. , (South Africa)
Type
Published Article
Journal
SA journal of radiology
Publication Date
Jan 01, 2023
Volume
27
Issue
1
Pages
2668–2668
Identifiers
DOI: 10.4102/sajr.v27i1.2668
PMID: 37292423
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

In developing countries, many diagnosed cases of ameloblastoma (AB) have a significant delay in receiving treatment because of patient factors and healthcare facility constraints. The radiologic progression of ABs with delayed treatment was analysed using panoramic radiographs and cone-beam computed tomography imaging. Histopathologically confirmed cases of AB with follow-up radiographs indicating no treatment were retrospectively reviewed over a study period of 10 years. Fifty-seven cases with 57 initial and 107 follow-up radiographs were included. Each follow-up radiograph was analysed for changes in borders, locularity, effects on surrounding structures and lesion size. There was a general increase in poorly-demarcated lesions, with seven cases transforming from an initial unilocular to a multilocular appearance. At follow-up, there was an increase in cortical thinning and cortical destruction. Ameloblastomas presented with a three-fold increase in average size from the initial to follow-up visits. Regression analysis showed a statistically significant relationship between lesion duration and length (p = 0.001). A statistically significant relationship existed between duration and overall lesion dimensions when only the first and last observations per patient were used (p = 0.044). Considering the aggressive nature and unlimited growth potential, ABs with delayed treatment may show extensive growth, complicating their eventual management. This study aimed to raise awareness of the importance of the timeous management of patients with AB by highlighting the detrimental effects of delayed treatment. © 2023. The Authors.

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