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Radioenzymatic assay for trimethoprim in very small serum samples.

Authors
  • R Yogev
  • C Melick
  • L Tan-Pong
Publication Date
Feb 01, 1985
Source
PMC
Keywords
License
Unknown

Abstract

A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-microliter serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 microliters) can be achieved.

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