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[Radiation-induced lung toxicity predictors after stereotactic radiation therapy for non-small cell lung carcinoma stage I].

Authors
  • Menoux, I1
  • Le Fèvre, C2
  • Noël, G3
  • Antoni, D3
  • 1 Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France. Electronic address: [email protected] , (France)
  • 2 Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France. , (France)
  • 3 Département universitaire de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, BP 42, 67065 Strasbourg cedex, France; EA 3430, laboratoire de radiobiologie, université de Strasbourg, fédération de médecine translationnelle de Strasbourg (FMTS), 67065 Strasbourg, France. , (France)
Type
Published Article
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Publication Date
Dec 01, 2018
Volume
22
Issue
8
Pages
826–838
Identifiers
DOI: 10.1016/j.canrad.2017.12.007
PMID: 30337050
Source
Medline
Keywords
Language
French
License
Unknown

Abstract

In case of refusal or contraindication for surgical management of a stage I non-small cell lung carcinoma, the validated alternative therapy is stereotactic irradiation. This technique reaches an equivalent tumour control rate than surgery and significantly higher than conventional radiotherapy. One of the dreaded complications is radiation induced lung toxicity (radiation pneumonitis and lung fibrosis), especially when it is symptomatic, occurring in about 10 % of cases. This article is a literature review of this complication's predictive factors. Copyright © 2018 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

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