Affordable Access

Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.

Authors
Type
Published Article
Journal
European journal of clinical pharmacology
Publication Date
Volume
59
Issue
1
Pages
23–28
Identifiers
PMID: 12743670
Source
Medline
License
Unknown

Abstract

The MR of quinine in plasma or urine may serve as a stable measure of the activity of CYP3A4 in man. These results together with in vitro data show that quinine is also a specific CYP3A4 probe.

Statistics

Seen <100 times